RELEASE OF SUPEROXIDE DISMUTASE FROM UMBILICAL VEINS BY LOW DOSE HEPARIN USED IN INTRAARTERIAL INFUSIONS. † 890

Superoxide dismutase Superoxide dismutase

Heparin-induced release of extracellular superoxide dismutase to human blood plasma.

Extracellular superoxide dismutase (SOD) has previously been shown to be the major SOD isoenzyme in extracellular fluids. Upon chromatography on heparin-Sepharose it was separated into three fractions: A, without affinity; B, with intermediate affinity; and C, with relatively strong heparin affinity. Intravenous injection of heparin leads to a prompt increase in plasma extracellular-superoxide-...

Superoxide radical concentration and superoxide dismutase (SOD) enzyme activity in varicose veins.

The aim of this study is to measure the level of both the superoxide dismutase (SOD) enzyme and its substrate, superoxide radicals, in the wall of varicose veins. A total of 44 vein specimens were collected from 24 patients who underwent surgery for varicose veins at Asir Central Hospital (ACH), Abha, Saudi Arabia during the period from October 1999 to November 2000. The patients were 4 males a...

Prophylactic low-dose heparin by jet injection.

graphic deterioration, in the patient and others affected by aerosols of contaminated water in other factories2 3 no radiographic changes were evident after several years' exposure, and no functional abnormalities persisted when away from work. Furthermore, the symptoms were prominent in the early part of the week, improving while continuing at work, but recurring on return to work after an abs...

Effect of superoxide dismutase‑entrapped liposomes and protein transduction domain‑superoxide dismutase on human umbilical vein endothelial cells.

Superoxide dismutases (SOD) are able to remove the superoxide anion free radicals produced by environmental stress and thereby protect cells from being injured by reactive oxygen species. However, SOD is unable to transduce automatically across cell membranes. Protein transduction domains (PTDs) are peptides able to mediate protein delivery into cells and were first observed in the HIV‑1 Tat pr...